TargetMol

Sphingosine-1-phosphate

Product Code:
 
TAR-T21500
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T21500-1mg1mg£311.00
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Further Information

Bioactivity:
Sphingosine-1-phosphate is an agonist for S1P1-5 receptors and a ligand for GPR3, GPR6, GPR12.Sphingosine-1-phosphate is an intracellular second messenger that mobilises Ca2+ as an extracellular ligand for G-protein coupled receptors. Sphingosine-1-phosphate is an important lipid mediator generated from sphingosine (HY-113498) or other membrane phospholipids.
CAS:
26993-30-6
Molecular Weight:
379.47
Pathway:
GPCR/G Protein|Metabolism
Purity:
0.98
SMILES:
[C@@H]([C@@H](/C=C/CCCCCCCCCCCCC)O)(COP(=O)(O)O)N
Target:
LPL Receptor|Endogenous Metabolite|S1P Receptor

References

Uhlenbrock K, et al. Sphingosine 1-phosphate is a ligand of the human gpr3, gpr6 and gpr12 family of constitutively active G protein-coupled receptors. Cell Signal. 2002 Nov;14(11):941-53. Sanchez T, et al. Structural and functional characteristics of S1P receptors. J Cell Biochem. 2004 Aug 1;92(5):913-22. An S, et al. Transduction of intracellular calcium signals through G protein-mediated activation of phospholipase C by recombinant sphingosine 1-phosphate receptors. Mol Pharmacol. 1999 May;55(5):787-94.