SNW1 Antibody / NCoA-62 / SKIP

Flow cytometry: 1-2ug/million cells,Immunofluorescence: 2-4ug/ml

Nuclear receptor coactivator NCOA62/SNW1 (also called Nuclear Protein SkiP, SKIIP, Ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.

Purified

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

A recombinant fragment of human SNW1 protein was used as the immunogen for the SNW1 antibody.

This SNW1 antibody is available for research use only.

Nucleus, cytoplasm

Protein A/G affinity

Q13573