ELK Biotechnology

Recombinant Mouse SAP (C-6His)

Product Code:
 
ELK-EPT196
Product Group:
 
Recombinant Proteins
Supplier:
 
ELK Biotechnology
Host Type:
 
Mouse
Regulatory Status:
 
RUO
Shipping:
 
The product is shipped on dry ice/polar packs.
Storage:
 
Store at -70°C, stable for 6 months after receipt. Store at -70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
 

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CodeSizePrice
ELK-EPT196-50ug50ug£758.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Accession:
P12246
Alternative Names:
APCS; PTX2; SAP; 9.5S alpha-1-glycoprotein; Serum amyloid P; MGC88159; PTX2serum amyloid P-component; SAP pentaxin-related
Apparent Molecular Weight:
28-32 KDa, reducing conditions
Background:
Pentraxin 2 (PTX2), also known as Serum amyloid P (SAP), is a highly conserved, naturally circulating plasma protein and a soluble pattern recognition receptor of the innate immune system. The unique binding activities indicated that it may play an important role in the removal of damaged tissue. PTX2 belongs to the pentraxin family, is universally present in amyloid deposits. Mouse with targeted deletion of the PTX2 gene shows retarded and reduced induction of experimental reactive systemic (AA type) amyloidosis confirmed that it does indeed contribute to pathogenesis of amyloidosis and is a valid therapeutic target. In recent discovery, PTX2 can be used as a powerful antifibrotic agent to regulate certain monocyte differentiation states.
Endotoxin:
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Molecular Weight:
24.9 KDa
Purity:
Greater than 95% as determined by reducing SDS-PAGE.