Diaclone

Mouse Anti-Human IL-12 p40 BioActive Antibody, Clone B-P24, Azide free

Product Code:
 
855.130.000
Product Group:
 
Primary Antibodies
Supplier:
 
Diaclone
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
B-P24
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Functional Study
 

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855.130.000200ug/200ul£232.00
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  • Further Information
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Further Information

Activity:
Inhibits IL-12 induced proliferation on PHA and IL-2 activated lymphocytes
Antigen:
IL-12p40+p70
Antigen Synonyms:
IL-12/IL23p40 IL-12p70
Conjugate:
Azide free
Format:
Azide free
Hybridoma:
Myeloma X63/AG.8653 x Balb/c spleen cells
Immunisation:
Recombinant human IL-12
Reactivity:
Human
Research Area:
Cytokines / Growth FactorsInnate Immunity
Specificity:
Recognises both natural and recombinant p40 subunit alone and in its IL-12 form (associated with p35) and in its IL-23 form(associated with p19)

References

  1. Nagai T. et al. J Immunol.2003; 171(10): 5233-43.. Timing of IFN-beta exposure during human dendritic cell maturation and naive Th cell stimulation has contrasting effects on Th1 subset generation: a role for IFN-beta-mediated regulation of IL-12 family cytokines and IL-18 in naive Th cell differentiation. https://www.ncbi.nlm.nih.gov/pubmed/14607924