NSJ Bioreagents

ATRX Antibody / RAD54

Product Code:
 
NSJ-V3808SAF
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG1 kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
23c
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
 
Store the ATRX antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
1 / 1
SDS-PAGE analysis of purified, BSA-free ATRX antibody (clone 23c) as confirmation of integrity and purity.

SDS-PAGE analysis of purified, BSA-free ATRX antibody (clone 23c) as confirmation of integrity and purity.

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NSJ-V3808SAF-100UG100 ug£534.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Application Details:
ELISA: 2-4ug/ml for coating (order BSA/sodium azide free format)
Application Note:
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the ATRX antibody to be titered up or down for optimal performance.
Description:
ATRX is a member of the Snf2 family of helicase/ATPases, which contribute to the remodeling of the nucelosome structure in an ATP-dependent manner, and facilitate the initiation of transcription and replication. Structurally, it contains a PHD zinc finger motif. ATRX is regulated throughout the cell cycle where it is differentially distributed within the nucleus. During interphase, it predominately associates with the nuclear matrix, while during mitosis, ATRX localizes with condensed chromatin. At the onset of M phase, phosphorylation rapidly induces this redistribution of ATRX to the short arms of human acrocentric chromosomes, where it then specifically complexes with heterochromatin protein 1 α to mediate chromosomal segregation. Mutations in the gene correlate with a high incidence of severe X-linked form of syndromal mental retardation associated with alpha-thalassemia or ATRX syndrome.
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
Recombinant human ATRX protein was used as the immunogen for this ATRX antibody.
Limitation:
This ATRX antibody is available for research use only.
Localization:
Nuclear
Purity:
Protein G affinity chromatography
Uniprot #:
P46100

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