NSJ Bioreagents

BTLA Antibody / CD272

Product Code:
 
NSJ-V7708SAF
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG2b kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
BTLA/1528
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
 
Store the BTLA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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SDS-PAGE analysis of purified, BSA-free BTLA antibody (clone BTLA/1528) as confirmation of integrity and purity.
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SDS-PAGE analysis of purified, BSA-free BTLA antibody (clone BTLA/1528) as confirmation of integrity and purity.

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NSJ-V7708SAF-100UG100 ug£534.00
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Further Information

Application Details:
ELISA (order BSA-free format for coating)
Application Note:
Optimal dilution of the antibody should be determined by the researcher.
Description:
B and T lymphocyte attenuator (BTLA) is an immunoglobulin domain-containing glycoprotein whose expression is induced during T-cell activation. BTLA is similar to CTLA-4 and PD-1, all of which are coinhibitory receptors belonging to the CD28 family. However, unlike CTLA-4 and PD-1, BTLA does not interact with B7-Ig family counter receptors. Rather, the herpesvirus entry mediator (HVEM), a TNF receptor, acts as a molecular switch that modulates T-cell activation by propagating inhibitory signals through BTLA. The BTLAHVEM interaction is conserved between Mouse and human, suggesting that this system is an important pathway regulating lymphocyte activation.
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
Recombinant extracellular human CD272/BTLA protein was used as the immunogen for this BTLA antibody.
Limitation:
This BTLA antibody is available for research use only.
Purity:
Protein G affinity chromatography

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