NSJ Bioreagents

OLIG2 Antibody

Product Code:
 
NSJ-V3822SAF
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG1 kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
ODTF2-1
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
 
After reconstitution the OLIG2 antibody can be stored for up to one month at 4oC. For long-term aliquot and store at -20oC. Avoid repeated freezing and thawing.
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IHC testing of FFPE human cerebellum with OLIG2 antibody (clone ODTF2-1). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min followed by cooling at RT for 20 min.

IHC testing of FFPE human cerebellum with OLIG2 antibody (clone ODTF2-1). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min followed by cooling at RT for 20 min.

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NSJ-V3822SAF-100UG100 ug£534.00
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This product comes from: United States.
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Further Information

Application Details:
IHC (FFPE): 1-2ug/ml for 30 min at RT
Application Note:
Optimal dilution of the OLIG2 antibody should be determined by the researcher.
Description:
Olig2, a basic helix-loop-helix transcription factor, is involved in oligodendroglial specification. Olig2 expression has been reported in most glial tumors, such as oligodendrogliomas and astrocytomas. Although more than half of glioblastomas are positive for Olig2, expression is very weak in terms of both percentage of labeled cells and intensity. No Olig2 expression has been found in the non-glial tumors including neuro-epithelial tumors, ependymomas, sub-ependymomas, medulloblastomas, and non-neuroepithelial tumors, such as CNS lymphomas, meningiomas, schwannomas, atypical teratoid / rhabdoid tumor, and haemangioblastomas. Compared to the strong staining seen in glioma samples, a weak expression is observed in non-tumoral brain tissue (gliosis).
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
A portion of amino acids 1-141 from the human protein was used as the immunogen for this OLIG2 antibody.
Limitation:
This OLIG2 antibody is available for research use only.
Localization:
Nuclear
Purity:
Protein G affinity
Uniprot #:
Q13516

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