NSJ Bioreagents

CNGB3 Antibody

Product Code:
 
NSJ-R36477
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Caprine (Goat)
Antibody Isotype:
 
Goat Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
 
Aliquot and store the CNGB3 antibody at -20oC.
1 / 2
IHC testing of FFPE human retinal with CNGB3 antibody at 2ug/ml. Staining of the pigmented epithelial cells is seen.~
2 / 2
IHC testing of FFPE human retinal without CNGB3 antibody (negative control).
❮❯

IHC testing of FFPE human retinal with CNGB3 antibody at 2ug/ml. Staining of the pigmented epithelial cells is seen.~
IHC testing of FFPE human retinal without CNGB3 antibody (negative control).

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CodeSizePrice
NSJ-R36477-100UG100 ug£535.00
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This product comes from: United States.
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Further Information

Application Details:
IHC (FFPE): 2-4ug/ml,ELISA (peptide) LOD: 1:8000
Application Note:
Optimal dilution of the CNGB3 antibody should be determined by the researcher.
Description:
Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. Cyclic nucleotide-gated cation channel beta-3 can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficiency of the channel when coexpressed with CNGA3 (By similarity). Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones. [UniProt]
Format:
Antigen affinity purified
Formulation:
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide
Immunogen:
Amino acids ESDDKPTEHYYR were used as the immunogen for this CNGB3 antibody.
Limitation:
This CNGB3 antibody is available for research use only.
Purity:
Antigen affinity
Uniprot #:
Q9NQW8

Documents