NSJ Bioreagents

LARGE Antibody / Like acetylglucosaminyltransferase

Product Code:
 
NSJ-F53896
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Aliquot the LARGE antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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Western blot testing of Jurkat cell lysate with LARGE antibody at 1:2000. Predicted molecular weight: 88 kDa.

Western blot testing of Jurkat cell lysate with LARGE antibody at 1:2000. Predicted molecular weight: 88 kDa.

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CodeSizePrice
NSJ-F53896-0.05ML0.05 ml£260.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Application Details:
Western blot: 1:1000-2000
Description:
Bifunctional glycosyltransferase with both xylosyltransferase and beta-1,3-glucuronyltransferase activities involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine- beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1). Phosphorylated O- mannosyl trisaccharid is required for binding laminin G-like domain-containing extracellular proteins with high affinity and plays a key role in skeletal muscle function and regeneration. LARGE elongates the glucuronyl-beta-1,4-xylose-beta disaccharide primer structure initiated by B3GNT1/B4GAT1 by adding repeating units [-3-Xylose-alpha-1,3-GlcA-beta-1-] to produce a heteropolysaccharide.
Format:
Antigen affinity purified
Formulation:
In 1X PBS, pH 7.4, with 0.09% sodium azide
Gene ID #:
9215
Immunogen:
A portion of amino acids 365-398 from the human protein was used as the immunogen for the LARGE antibody.
Limitation:
This LARGE antibody is available for research use only.
Purity:
Antigen affinity
Uniprot #:
O95461

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