Elabscience

Recombinant Human UBE2I/UBC9 Protein

Product Code:
 
PKSH030701
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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PKSH030701-100ug100ug£832.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
UBE2I;UBC9
Accession:
P63279
Background:
UBE2I is a member of the ubiquitin-conjugating E2 family whose members perform the second step in the ubiquitination reaction. Initially identified as the main process for protein degradation; ubiquitination is believed nowadays to be crucial for a wider range of cellular processes. The outcome of the ubiquitin-conjugation reaction; and thereby the fate of the substrate; is heavily dependent on the number of ubiquitin molecules attached and how these ubiquitin molecules are inter-connected. To deal with this complexity and to allow adequate ubiquitination in time and space; a highly sophisticated conjugation machinery has been developed. In a sequential manner; ubiquitin becomes activated by an ubiquitin-activating enzyme (E1); which then transfers the ubiquitin to a group of ubiquitin-conjugating enzymes (E2s). Next; ubiquitin-loaded E2s are interacting with ubiquitin protein ligases (E3s) and ubiquitin is conjugated to substrates on recruitment by the E3. These three key enzymes are operating in a hierarchical system; wherein two E1s and 35 E2s have been found and hundreds of E3s have been identified in humans.
Calculated MW:
18 kDa
Expression Host:
E.coli
Formulation:
Lyophilized from sterile PBS, 10% glycerol, 2mM DTT, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
None
ObservedMW:
18 kDa
Purity:
> 90 % as determined by reducing SDS-PAGE.
Sequence:
Met 1-Ser 158
Target Synonym:
SUMO-Conjugating Enzyme UBC9;SUMO-Protein Ligase;Ubiquitin Carrier Protein 9;Ubiquitin Carrier Protein I;Ubiquitin-Conjugating Enzyme E2 I;Ubiquitin-Protein Ligase I;p18;UBE2I;UBC9;UBCE9
UNIProt ID:
P63279

Documents