Elabscience

Recombinant Human CD147/BSG/Basigin protein (His tag)

Product Code:
 
PDEH100300
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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CodeSizePrice
PDEH100300-20ug20ug£113.00
Quantity:
PDEH100300-100ug100ug£140.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
CD147;BSG;Basigin
Accession:
P35613
Background:
CD147/EMMPRIN (Extracellular Matrix Metalloproteinase Inducer); also known as Basigin (BSG); is a transmembrane glycoprotein with different forms resulted from different modes of glycosylation and N-terminal sequence variants. It is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis; embryo implantation; neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells; and thereby promotes invasion; metastasis; growth and survival of malignant cells. Furthermore; CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction. Recently; CD147 displays increased expression in many cancers; and it has been previously demonstrated to participate in cancer metastasis and progression. Thus; CD147 and its antibody are used as an effective treatment for malignant cancers.
Calculated MW:
20.35 kDa
Expression Host:
E.coli
Formulation:
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
N-His
ObservedMW:
25 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Glu 138-Ala 323
Target Synonym:
Basigin;5F7;Collagenase Stimulatory Factor;Extracellular Matrix Metalloproteinase Inducer;EMMPRIN;Leukocyte Activation Antigen M6;OK Blood Group Antigen;Tumor Cell-Derived Collagenase Stimulatory Factor;TCSF;CD147;BSG
UNIProt ID:
P35613

Documents