Elabscience

Recombinant Human CD62L/L-Selectin protein (His tag)

Product Code:
 
PDEH100294
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
 

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CodeSizePrice
PDEH100294-20ug20ug£113.00
Quantity:
PDEH100294-100ug100ug£140.00
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This product comes from: China.
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Further Information

Abbreviation:
CD62L;L-Selectin
Accession:
P30836
Background:
L-Selectin (also known as Leukocyte Selectin, LAM-1, LECAM-1, LECCAM-1, TQ1, Leu-8, MEL-14 antigen, DREG, lymph node homing receptor, CD62L), a member of the Selectin family, is a cell surface glycoprotein expressed constitutively on a wide variety of leukocytes. Two forms of L-Selectin have been reported, apparently arising as a result of post-translational modifications. The lymphocyte form shows an apparent molecular weight of 74 kDa, while the neutrophil form is 90 - 100 kDa. Human and mouse L-Selectin share 76% amino acid (aa) sequence homology.L-Selectin plays a role in the migration of lymphocytes into peripheral lymph nodes and sites of chronic inflammation, and of neutrophils into acute inflammatory sites. Acting in cooperation with P-Selectin and E-Selectin, L-Selectin mediates the initial interaction of circulating leukocytes with endothelial cells that produces a characteristic "rolling" of the leukocytes on the endothelium. This initial interaction, also involving ICAM-1 and VCAM-1, leads eventually to extravasation of the white blood cell through the blood vessel wall into the extracellular matrix tissue.
Calculated MW:
32.23 kDa
Expression Host:
E.coli
Formulation:
Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
N-His
ObservedMW:
39 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Trp 39-Asn 332
Target Synonym:
L-Selectin;Sell;CD62 antigen-like family member L;Leukocyte adhesion molecule 1 (LAM-1);Leukocyte-endothelial cell adhesion molecule 1;Lymph node homing receptor;Lymphocyte antigen 22 (Ly-22);Lymphocyte surface MEL-14 antigen;CD62L
UNIProt ID:
P30836

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