Elabscience

Fbx32/FBOX32 Polyclonal Antibody

Product Code:
 
E-AB-93393
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunofluorescence (IF)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
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Western blot analysis of extracts of RD cells using Fbx32/FBOX32 Polyclonal Antibody at 1:1000 dilution.
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Immunofluorescence analysis of mouse skeletal muscle using Fbx32/FBOX32 Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
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Western blot analysis of extracts of RD cells using Fbx32/FBOX32 Polyclonal Antibody at 1:1000 dilution.
Immunofluorescence analysis of mouse skeletal muscle using Fbx32/FBOX32 Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

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E-AB-93393-60uL60uL£210.00
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E-AB-93393-120uL120uL£291.00
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E-AB-93393-200uL200uL£431.00
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Further Information

Abbreviation:
Fbx32/FBOX32
Background:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
30kDa/41kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000,IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human Fbx32/FBOX32
ObservedMW:
40KDa
Purification method:
Affinity purification
Target Synonym:
FBXO32;Fbx32;MAFbx
UNIProt ID:
Q969P5

Documents