Elabscience

NRAS Polyclonal Antibody

Product Code:
 
E-AB-92783
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
1 / 3
Western blot analysis of extracts of Mouse brain using NRAS Polyclonal Antibody at 1:1000 dilution.
2 / 3
Immunofluorescence analysis of NIH/3T3 cells using NRAS Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
3 / 3
Immunofluorescence analysis of U2OS cells using NRAS Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
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Western blot analysis of extracts of Mouse brain using NRAS Polyclonal Antibody at 1:1000 dilution.
Immunofluorescence analysis of NIH/3T3 cells using NRAS Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Immunofluorescence analysis of U2OS cells using NRAS Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

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CodeSizePrice
E-AB-92783-60uL60uL£210.00
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E-AB-92783-120uL120uL£291.00
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E-AB-92783-200uL200uL£431.00
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Further Information

Abbreviation:
NRAS
Background:
This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
21kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IF 1:50-1:200
Immunogen:
A synthetic peptide of human NRAS
ObservedMW:
21KDa
Purification method:
Affinity purification
Target Synonym:
NRAS;ALPS4;CMNS;N-ras;NCMS;NRAS1;NS6
UNIProt ID:
P01111

Documents