Elabscience

PTPRF Polyclonal Antibody

Product Code:
 
E-AB-92649
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
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Western blot analysis of extracts of various cell lines using PTPRF Polyclonal Antibody at 1:1000 dilution.
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Western blot analysis of extracts of various cell lines using PTPRF Polyclonal Antibody at 1:1000 dilution.

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E-AB-92649-60uL60uL£210.00
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E-AB-92649-120uL120uL£291.00
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E-AB-92649-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
PTPRF
Background:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
211kDa/212kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human PTPRF
ObservedMW:
150kDa
Purification method:
Affinity purification
Target Synonym:
PTPRF;BNAH2;LAR
UNIProt ID:
P10586

Documents