Elabscience

OGG1 Polyclonal Antibody

Product Code:
 
E-AB-92460
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
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Western blot analysis of extracts of HepG2 cells using OGG1 Polyclonal Antibody at 1:1000 dilution.
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Western blot analysis of extracts of HepG2 cells using OGG1 Polyclonal Antibody at 1:1000 dilution.

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E-AB-92460-60uL60uL£210.00
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E-AB-92460-120uL120uL£291.00
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E-AB-92460-200uL200uL£431.00
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Further Information

Abbreviation:
OGG1
Background:
This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
22kDa/36kDa/38kDa/39kDa/40kDa/45kDa/47kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:1000
Immunogen:
Recombinant fusion protein of human OGG1
ObservedMW:
36kDa
Purification method:
Affinity purification
Target Synonym:
OGG1;HMMH;HOGG1;MUTM;OGH1
UNIProt ID:
O15527

Documents