Elabscience

E2A Polyclonal Antibody

Product Code:
 
E-AB-92455
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
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Western blot analysis of various lysates using E2A Polyclonal Antibody at 1:1000 dilution.
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Western blot analysis of various lysates using E2A Polyclonal Antibody at 1:1000 dilution.

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CodeSizePrice
E-AB-92455-60uL60uL£210.00
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E-AB-92455-120uL120uL£291.00
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E-AB-92455-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
E2A
Background:
This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1), childhood leukemia (t(19;19), with TFPT) and acute leukemia (t(12;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
67kDa/68kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human E2A
ObservedMW:
75KDa
Purification method:
Affinity purification
Target Synonym:
TCF3;AGM8;E2A;E47;ITF1;TCF-3;VDIR;bHLHb21
UNIProt ID:
P15923

Documents