Elabscience

Enpp1 Polyclonal Antibody

Product Code:
 
E-AB-91948
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
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Immunofluorescence analysis of C6 cells using Enpp1 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
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Immunofluorescence analysis of C6 cells using Enpp1 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

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CodeSizePrice
E-AB-91948-60uL60uL£210.00
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E-AB-91948-120uL120uL£291.00
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E-AB-91948-200uL200uL£431.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
Enpp1
Background:
This gene encodes a member of the nucleoside pyrophosphatase/phosphodiesterase family of enzymes that catalyzes the hydrolysis of pyrophosphate and phosphodiester bonds in nucleotide triphosphates and oligonucleotides, respectively, to generate nucleoside 5'-monophosphates. The encoded protein is a type II transmembrane glycoprotein that negatively regulates bone mineralization. Mice harboring a nonsense mutation in this gene, termed tiptoe walking (ttw), exhibit ectopic ossification of the spinal ligaments. The encoded protein binds to the insulin receptor, inhibits downstream signaling events and induces insulin resistance and glucose tolerance. This gene is located adjacent to a paralog on chromosome 10. Alternative splicing results in multiple transcript variants encoding different isoforms.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
103kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IF 1:50-1:200
Immunogen:
Recombinant fusion protein of mouse Enpp1
ObservedMW:
120kDa/170kDa
Purification method:
Affinity purification
Target Synonym:
Pca;ttw;twy;M6S1;NPP1;Npps;PC-1;Ly-41;Pca-1;Pdnp1;C76301;CD203c;E-NPP1;E-NPP 1;AI428932;4833416E15Rik;Enpp1
UNIProt ID:
G3X9S2

Documents