Elabscience

KNSTRN Polyclonal Antibody

Product Code:
 
E-AB-90794
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
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Western blot analysis of extracts of various cell lines using KNSTRN Polyclonal Antibody at 1:1000 dilution.
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Western blot analysis of extracts of various cell lines using KNSTRN Polyclonal Antibody at 1:1000 dilution.

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E-AB-90794-60uL60uL£210.00
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E-AB-90794-120uL120uL£291.00
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E-AB-90794-200uL200uL£431.00
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Further Information

Abbreviation:
KNSTRN
Background:
Essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase. Promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5-kinastrin (SKAP complex promotes stable microtubule-kinetochore attachments. Required for kinetochore oscillations and dynamics of microtubule plus-ends during live cell mitosis, possibly by forming a link between spindle microtubule plus-ends and mitotic chromosomes to achieve faithful cell division. May be involved in UV-induced apoptosis via its interaction with PRPF19; however, these results need additional evidences.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
26kDa/31kDa/35kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human KNSTRN
ObservedMW:
34kDa
Purification method:
Affinity purification
Target Synonym:
KNSTRN;C15orf23;HSD11;SKAP;TRAF4AF1
UNIProt ID:
Q9Y448

Documents