Elabscience

MSL2 Polyclonal Antibody

Product Code:
 
E-AB-90576
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
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Western blot analysis of extracts of various cell lines using MSL2 Polyclonal Antibody at 1:3000 dilution.

Western blot analysis of extracts of various cell lines using MSL2 Polyclonal Antibody at 1:3000 dilution.

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CodeSizePrice
E-AB-90576-60uL60uL£210.00
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E-AB-90576-120uL120uL£291.00
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E-AB-90576-200uL200uL£431.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
MSL2
Background:
Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at 'Lys-35' (H2BK34Ub, but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histone H3 methylation at 'Lys-4' (H3K4me and 'Lys-79' (H3K79me and leads to gene activation, including that of HOXA9 and MEIS1.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
54kDa/62kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human MSL2
ObservedMW:
62kDa
Purification method:
Affinity purification
Target Synonym:
MSL2;MSL-2;MSL2L1;RNF184
UNIProt ID:
Q9HCI7

Documents