Elabscience

MAPKBP1 Polyclonal Antibody

Product Code:
 
E-AB-90428
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
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Western blot analysis of extracts of various cell lines using MAPKBP1 Polyclonal Antibody at 1:1000 dilution.
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Western blot analysis of extracts of various cell lines using MAPKBP1 Polyclonal Antibody at 1:1000 dilution.

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E-AB-90428-60uL60uL£210.00
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E-AB-90428-120uL120uL£291.00
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E-AB-90428-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
MAPKBP1
Background:
This gene encodes a scaffold protein that regulates the JNK (c-Jun N-terminal kinase) and NOD2 (nucleotide-binding oligomerization domain-containing protein 2) signaling pathways. The encoded protein interacts with another related JNK pathway scaffold protein, WDR62, via a conserved dimerization domain, and enhances JNK signaling. This protein may play a role in bacterial immunity by binding to the NOD2 receptor and negatively regulating downstream antibacterial and pro-inflammatory signaling. Mutations in this gene that impair cellular localization of the encoded protein cause a form of nephronophthisis, an autosomal-recessive kidney disorder, in human patients.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
23kDa/109kDa/134kDa/149kDa/163kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
A synthetic peptide of human MAPKBP1
ObservedMW:
164kDa
Purification method:
Affinity purification
Target Synonym:
MAPKBP1;JNKBP-1;JNKBP1;NPHP20
UNIProt ID:
O60336

Documents