Elabscience

HLA-DOB Polyclonal Antibody

Product Code:
 
E-AB-90358
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
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Western blot analysis of extracts of various cell lines using HLA-DOB Polyclonal Antibody at 1:3000 dilution.
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Western blot analysis of extracts of various cell lines using HLA-DOB Polyclonal Antibody at 1:3000 dilution.

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E-AB-90358-60uL60uL£210.00
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E-AB-90358-120uL120uL£291.00
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E-AB-90358-200uL200uL£431.00
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Further Information

Abbreviation:
HLA-DOB
Background:
HLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
30kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000
Immunogen:
Recombinant fusion protein of human HLA-DOB
ObservedMW:
31kDa
Purification method:
Affinity purification
Target Synonym:
HLA-DOB;DOB;HLA_DOB;major histocompatibility complex;class II;DO beta
UNIProt ID:
P13765

Documents