Elabscience

RFTN1 Polyclonal Antibody

Product Code:
 
E-AB-90163
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
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Western blot analysis of extracts of various cell lines using RFTN1 Polyclonal Antibody at 1:1000 dilution.

Western blot analysis of extracts of various cell lines using RFTN1 Polyclonal Antibody at 1:1000 dilution.

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CodeSizePrice
E-AB-90163-60uL60uL£210.00
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E-AB-90163-120uL120uL£291.00
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E-AB-90163-200uL200uL£431.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
RFTN1
Background:
Involved in protein trafficking via association with clathrin and AP2 complex. Upon bacterial lipopolysaccharide stimulation, mediates internalization of TLR4 to endosomes in dendritic cells and macrophages; and internalization of poly(I:C to TLR3-positive endosomes in myeloid dendritic cells and epithelial cells; resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production. Involved in T-cell antigen receptor-mediated signaling by regulating tyrosine kinase LCK localization, T-cell dependent antibody production and cytokine secretion (By similarity. May regulate B-cell antigen receptor-mediated signaling. May play a pivotal role in the formation and/or maintenance of lipid rafts.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
63kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human RFTN1
ObservedMW:
70kDa
Purification method:
Affinity purification
Target Synonym:
RFTN1;MIG2;PIB10;PIG9;RAFTLIN;raftlin
UNIProt ID:
Q14699

Documents