Elabscience

MCFD2 Polyclonal Antibody

Product Code:
 
E-AB-90146
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
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Western blot analysis of extracts of various cell lines using MCFD2 Polyclonal Antibody at 1:1000 dilution.
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Western blot analysis of extracts of various cell lines using MCFD2 Polyclonal Antibody at 1:1000 dilution.

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CodeSizePrice
E-AB-90146-60uL60uL£210.00
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E-AB-90146-120uL120uL£291.00
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E-AB-90146-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
MCFD2
Background:
This gene encodes a soluble luminal protein with two calmodulin-like EF-hand motifs at its C-terminus. This protein forms a complex with LMAN1 (lectin mannose binding protein 1; also known as ERGIC-53) that facilitates the transport of coagulation factors V (FV) and VIII (FVIII) from the endoplasmic reticulum to the Golgi apparatus via an endoplasmic reticulum Golgi intermediate compartment (ERGIC). Mutations in this gene cause combined deficiency of FV and FVIII (F5F8D); a rare autosomal recessive bleeding disorder characterized by mild to moderate bleeding and coordinate reduction in plasma FV and FVIII levels. This protein has also been shown to maintain stem cell potential in adult central nervous system and is a marker for testicular germ cell tumors. The 3' UTR of this gene contains a transposon-like human repeat element named 'THE 1'. A processed RNA pseudogene of this gene is on chromosome 6p22.1. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
10kDa/14kDa/16kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human MCFD2
ObservedMW:
16kDa
Purification method:
Affinity purification
Target Synonym:
MCFD2;F5F8D;F5F8D2;LMAN1IP;SDNSF
UNIProt ID:
Q8NI22

Documents