Elabscience

PATZ1 Polyclonal Antibody

Product Code:
 
E-AB-90051
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
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Western blot analysis of various lysates using PATZ1 Polyclonal Antibody at 1:2000 dilution.
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Western blot analysis of various lysates using PATZ1 Polyclonal Antibody at 1:2000 dilution.

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CodeSizePrice
E-AB-90051-60uL60uL£210.00
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E-AB-90051-120uL120uL£291.00
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E-AB-90051-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
PATZ1
Background:
The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1;22)(p36.1;q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
57kDa/69kDa/74kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:4000
Immunogen:
Recombinant fusion protein of human PATZ1
ObservedMW:
74KDa
Purification method:
Affinity purification
Target Synonym:
PATZ1;MAZR;PATZ;RIAZ;ZBTB19;ZNF278;ZSG;dJ400N23
UNIProt ID:
Q9HBE1

Documents