Elabscience

STAT3 Polyclonal Antibody

Product Code:
 
E-AB-68272
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of various cell lines using STAT3 Polyclonal Antibody at 1:1000 dilution.
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Western blot analysis of extracts of various cell lines using STAT3 Polyclonal Antibody at 1:1000 dilution.

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CodeSizePrice
E-AB-68272-60uL60uL£210.00
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E-AB-68272-120uL120uL£291.00
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E-AB-68272-200uL200uL£431.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
STAT3
Background:
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
83kDa/87kDa/88kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human STAT3
ObservedMW:
88kDa
Purification method:
Affinity purification
Target Synonym:
ADMIO;ADMIO1;APRF;HIES;STAT3;Stat3
UNIProt ID:
P40763

Documents