Elabscience

AIFM1 Polyclonal Antibody

Product Code:
 
E-AB-10123
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
-20°C
1 / 3
Western Blot analysis of NIH/3T3 , Hela and 293T cell using AIFM1 Polyclonal Antibody at dilution of 1:600
2 / 3
Immunohistochemistry of paraffin-embedded Human liver cancer using AIFM1 Polyclonal Antibody at dilution of 1:30
3 / 3
Immunohistochemistry of paraffin-embedded Human colon cancer using AIFM1 Polyclonal Antibody at dilution of 1:30
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Western Blot analysis of NIH/3T3 , Hela and 293T cell using AIFM1 Polyclonal Antibody at dilution of 1:600
Immunohistochemistry of paraffin-embedded Human liver cancer using AIFM1 Polyclonal Antibody at dilution of 1:30
Immunohistochemistry of paraffin-embedded Human colon cancer using AIFM1 Polyclonal Antibody at dilution of 1:30

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E-AB-10123-20uL20uL£125.00
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E-AB-10123-60uL60uL£172.00
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E-AB-10123-120uL120uL£237.00
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E-AB-10123-200uL200uL£344.00
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This product comes from: China.
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Further Information

Abbreviation:
AIFM1
Background:
This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
67kDa
Concentration:
0.2 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:25-1:100
Immunogen:
Recombinant protein of human AIFM1
Purification method:
Affinity purification
Target Synonym:
AIFM1;AIFM1;Apoptosis inducing factor 1;mitochondrial;Apoptosis inducing factor;Apoptosis inducing factor;mitochondrion associated;1;Apoptosis-inducing factor 1;CMTX4;COWCK;COXPD6;Harlequin;Hq;mAIF;MGC111425;MGC5706;mitochondrial;Neuropathy;axonal motor-sensory;with deafness and mental retardation;neuropathy;axonal;motor-sensory with deafness and mental retardation (Cowchock syndrome);PDCD 8;PDCD8;Programmed cell death 8 (apoptosis inducing factor);Programmed cell death 8;Programmed cell death 8 isoform 1;Programmed cell death 8 isoform 2;Programmed cell death 8 isoform 3;Programmed cell death protein 8;Programmed cell death protein 8 mitochondrial;Programmed cell death protein 8 mitochondrial precursor;Programmed cell death protein 8 mitochondrial precursor;Striatal apoptosis inducing factor
UNIProt ID:
O95831

Documents