Elabscience

CHRNA7 Polyclonal Antibody

Product Code:
 
E-AB-12583
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
-20°C
1 / 3
Western Blot analysis of Mouse heart tissue using CHRNA7 Polyclonal Antibody at dilution of 1:700
2 / 3
Immunohistochemistry of paraffin-embedded Human liver cancer using CHRNA7 Polyclonal Antibody at dilution of 1:40
3 / 3
Immunohistochemistry of paraffin-embedded Human cervical cancer using CHRNA7 Polyclonal Antibody at dilution of 1:40
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Western Blot analysis of Mouse heart tissue using CHRNA7 Polyclonal Antibody at dilution of 1:700
Immunohistochemistry of paraffin-embedded Human liver cancer using CHRNA7 Polyclonal Antibody at dilution of 1:40
Immunohistochemistry of paraffin-embedded Human cervical cancer using CHRNA7 Polyclonal Antibody at dilution of 1:40

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E-AB-12583-20uL20uL£125.00
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E-AB-12583-60uL60uL£172.00
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E-AB-12583-120uL120uL£237.00
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E-AB-12583-200uL200uL£344.00
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Further Information

Abbreviation:
CHRFAM7A
Background:
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
46kDa
Concentration:
0.3 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:25-1:100
Immunogen:
Synthetic peptide of human CHRFAM7A
Purification method:
Affinity purification
Target Synonym:
7nAChR;a7 nicotinic acetylcholine receptor;acetylcholine receptor;neuronal nicotinic;alpha-7 subunit;ACHA7;AChR;Acra7;alpha 7 neuronal nicotinic acetylcholine receptor;alpha-7 nicotinic cholinergic receptor subunit;alpha7;cholinergic receptor;neuronal nicotinic;alpha polypeptide 7;cholinergic receptor;nicotinic;alpha 7 (neuronal);cholinergic receptor;nicotinic;alpha 7;cholinergic receptor;nicotinic;alpha polypeptide 7;CHRNA7;CHRNA7-2;NACHRA7;neuronal acetylcholine receptor protein;alpha-7 chain;Neuronal acetylcholine receptor subunit alpha-7
UNIProt ID:
P36544

Documents