Elabscience

HIF1AN Polyclonal Antibody

Product Code:
 
E-AB-13556
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
-20°C
1 / 3
Western Blot analysis of Mouse brain and liver tissue using HIF1AN Polyclonal Antibody at dilution of 1:200
2 / 3
Immunohistochemistry of paraffin-embedded Human esophagus cancer using HIF1AN Polyclonal Antibody at dilution of 1:40
3 / 3
Immunohistochemistry of paraffin-embedded Human brain  using HIF1AN Polyclonal Antibody at dilution of 1:40

Western Blot analysis of Mouse brain and liver tissue using HIF1AN Polyclonal Antibody at dilution of 1:200
Immunohistochemistry of paraffin-embedded Human esophagus cancer using HIF1AN Polyclonal Antibody at dilution of 1:40
Immunohistochemistry of paraffin-embedded Human brain  using HIF1AN Polyclonal Antibody at dilution of 1:40

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E-AB-13556-20uL20uL£125.00
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E-AB-13556-60uL60uL£172.00
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E-AB-13556-120uL120uL£237.00
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E-AB-13556-200uL200uL£344.00
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This product comes from: China.
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Further Information

Abbreviation:
HIF1AN
Background:
Factor inhibiting HIF-1 (FIH-1) exists as a homodimer and binds to HIF-1alpha. Specifically, FIH-1 operates as an asparaginyl hydroxylase. It catalyzes the hydroxylation of the beta-carbon of Asparagine residue 803 within the carboxy terminal transactivation domain of HIF-1alpha. This hydroxylation event blocks the association of HIF-1alpha with co-activators. FIH-1 also binds to von Hippel-Lindau (VHL) tumor suppressor protein, which represses transcriptional ac-tivity of HIF-1alpha. In transiently transfected human osteosarcoma cells, FIH-1 localizes to the cytoplasm.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
40kDa
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:300
Immunogen:
Synthetic peptide of human HIF1AN
Purification method:
Affinity purification
Target Synonym:
DKFZp762F1811;Factor inhibiting HIF-1;Factor inhibiting HIF1;FIH 1;FIH-1;FIH1;FLJ20615;FLJ22027 ;HIF1AN;HIF1N;Hypoxia inducible factor 1 alpha inhibitor;Hypoxia inducible factor 1 alpha subunit inhibitor;Hypoxia inducible factor asparagine hydroxylase;Hypoxia-inducible factor 1-alpha inhibitor;Hypoxia-inducible factor asparagine hydroxylase;Peptide aspartate beta dioxygenase
UNIProt ID:
Q9NWT6

Documents