Elabscience

NPHS2 Polyclonal Antibody

Product Code:
 
E-AB-16657
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
 
Ice packs
Storage:
 
-20°C
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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using NPHS2 Polyclonal Antibody at dilution 1:40
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Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using NPHS2 Polyclonal Antibody at dilution 1:40
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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using NPHS2 Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using NPHS2 Polyclonal Antibody at dilution 1:40

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E-AB-16657-20uL20uL£125.00
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E-AB-16657-60uL60uL£172.00
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E-AB-16657-120uL120uL£237.00
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E-AB-16657-200uL200uL£344.00
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  • Further Information
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Further Information

Abbreviation:
NPHS2
Background:
This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
1.4 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human NPHS2
Purification method:
Affinity purification
Target Synonym:
Nephrosis 2;idiopathic;steroid resistant (podocin);nephrosis 2;idiopathic;steroid resistant;NPHS2;NPHS2 gene;PDCN;PODO;Podocin;SRN1
UNIProt ID:
Q9NP85

Documents

References

  • https://www.tandfonline.com/doi/abs/10.1080/1354750X.2022.2157489