Elabscience

PERK Polyclonal Antibody

Product Code:
 
E-AB-32546
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
-20°C
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Western Blot analysis of Hela cells using PERK Polyclonal Antibody at dilution of 1:2000.
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Western Blot analysis of Hela cells using PERK Polyclonal Antibody at dilution of 1:2000.

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E-AB-32546-20uL20uL£125.00
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E-AB-32546-60uL60uL£172.00
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E-AB-32546-120uL120uL£237.00
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E-AB-32546-200uL200uL£344.00
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This product comes from: China.
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  • Further Information
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  • References
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Further Information

Abbreviation:
PERK
Background:
Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin D1.
Buffer:
PBS with 0.02% sodium azide,0.5% protective protein and 50% glycerol pH 7.4.
Calculated MW:
125kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000
Immunogen:
Synthesized peptide derived from the N-terminal region of human PERK
ObservedMW:
125kDa
Purification method:
Affinity purification
Target Synonym:
DKFZp781H1925;E2AK3;EC 2.7.11.1;Eif2ak3;Eukaryotic translation initiation factor 2 alpha kinase 3;Eukaryotic translation initiation factor 2-alpha kinase 3;Heme regulated EIF2 alpha kinase;HRI;HsPEK;Pancreatic eIF2 alpha kinase;Pancreatic eIF2-alpha kinase;PEK;PRKR like endoplasmic reticulum kinase;PRKR-like endoplasmic reticulum kinase;WRS
UNIProt ID:
Q9NZJ5

Documents

References

  • https://www.mdpi.com/1975256
  • https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0201986