TBX5 Polyclonal Antibody

TBX5

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene.

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

58kDa

0.8 mg/mL

Unconjugated

WB 1:200-1:1000, IHC 1:50-1:200

Synthetic peptide of human TBX5

Affinity purification

Holt Oram syndrome;HOS;T box 5;T box protein 5;T box transcription factor TBX 5;T box transcription factor TBX5;T-box protein 5;T-box transcription factor TBX5;TBX 5;TBX5;TBX5;Transcription factor T box 5

Q99593