Elabscience

TXNIP Polyclonal Antibody

Product Code:
 
E-AB-17495
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
 
Ice packs
Storage:
 
-20°C
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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TXNIP Polyclonal Antibody at dilution 1:50
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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TXNIP Polyclonal Antibody at dilution 1:50

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E-AB-17495-20uL20uL£125.00
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E-AB-17495-60uL60uL£172.00
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E-AB-17495-120uL120uL£237.00
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E-AB-17495-200uL200uL£344.00
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This product comes from: China.
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Further Information

Abbreviation:
TXNIP
Background:
May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1).
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.9 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:30-150, ELISA 1:2000-10000
Immunogen:
Synthetic peptide of human TXNIP
Purification method:
Affinity purification
Target Synonym:
THIF;VDUP1;HHCPA78;EST01027
UNIProt ID:
Q9H3M7

Documents