Elabscience

Recombinant Mouse CD64/FCGR1 Protein (His&AVI Tag), Biotinylated(Active)

Product Code:
 
PKSM040877
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Mouse
Regulatory Status:
 
RUO
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Samples are stable for up to twelve months from date of receipt at -70°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
 

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CodeSizePrice
PKSM040877-20ug20ug£667.00
Quantity:
PKSM040877-100ug100ug£1,432.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
CD64;FCGR1
Accession:
NP_034316.1
Activity:
1. Immobilized Rituximab (IgG1) at 1 ug/mL can bind Biotinylated Mouse CD64 recombinant protein, the EC50 is 20-50 ng/mL. 2. Labeling ratio of biotin to protein is 0.7-1 by the HABA assay.
Background:
High affinity immunoglobulin gamma Fc receptor I, also known as FCGR1 and CD64, is an integral membraneglycoprotein and a member of the immunoglobulin superfamily. CD64 is a high affinity receptor for the Fc region of IgG gamma and functions in both innate and adaptive immune responses. Receptors that recognize the Fc portion of IgG function in the regulation of immune response and are divided into three classes designated CD64, CD32, and CD16. CD64 is structurally composed of asignal peptidethat allows its transport to the surface of a cell, threeextracellularimmunoglobulin domainsof the C2-type that it uses to bind antibody, a hydrophobictransmembrane domain, and a short cytoplasmic tail. CD64 isconstitutivelyfound on only macrophages and monocytes, but treatment of polymorphonuclear leukocyteswith cytokines likeIFNγandG-CSFcan induce CD64 expression on these cells. The inactivation of the mouse CD64 resulted in a wide range of defects in antibody Fc-dependent functions. Mouse CD64 is an early participant in Fc-dependent cell activation and in the development of immune responses.
Calculated MW:
34.3 kDa
Conjugation:
Biotinylated
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His-AVI
ObservedMW:
50-55 kDa
Purity:
> 90 % as determined by reducing SDS-PAGE.
Sequence:
Met 1-Pro 297
Target Synonym:
AI323638;AV092959;CD64;FcgammaRI;IGGHAFC

Documents