Elabscience

PCNA Polyclonal Antibody

Product Code:
 
E-AB-10010
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western Blot analysis of Hela cell using Proliferating Cell Nuclear Antigen Polyclonal Antibody at dilution of 1:500
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Immunohistochemistry of paraffin-embedded Human gastic cancer using Proliferating Cell Nuclear Antigen Polyclonal Antibody at dilution of 1:44
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Immunohistochemistry of paraffin-embedded Human breast cancer using Proliferating Cell Nuclear Antigen Polyclonal Antibody at dilution of 1:44
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Western Blot analysis of Hela cell using Proliferating Cell Nuclear Antigen Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human gastic cancer using Proliferating Cell Nuclear Antigen Polyclonal Antibody at dilution of 1:44
Immunohistochemistry of paraffin-embedded Human breast cancer using Proliferating Cell Nuclear Antigen Polyclonal Antibody at dilution of 1:44

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E-AB-10010-20uL20uL£125.00
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E-AB-10010-60uL60uL£172.00
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E-AB-10010-120uL120uL£237.00
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E-AB-10010-200uL200uL£344.00
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  • Further Information
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Further Information

Abbreviation:
PCNA
Background:
This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Calculated MW:
29kDa
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200
Immunogen:
Recombinant protein of human PCNA
ObservedMW:
Refer to figures
Purification method:
Affinity purification
Target Synonym:
ATLD2;cb16;Cyclin;DNA polymerase delta auxiliary protein;etID36690.10;fa28e03;fb36g03;HGCN8729;MGC8367;Mutagen-sensitive 209 protein;OTTHUMP00000030189;OTTHUMP00000030190;PCNA;Pcna/cyclin;PCNA;PCNAR;Polymerase delta accessory protein;Proliferating cell nuclear antigen;wu:fa28e03;wu:fb36g03
UNIProt ID:
P12004

Documents

References

  • https://www.sciencedirect.com/science/article/pii/S0006295221003336