Elabscience

BECN1 Monoclonal Antibody

Product Code:
 
E-AB-22139
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Mouse
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
Clone:3C6
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
1 / 2
Western Blot analysis of 1) 293T, 2) C2C12, 3) Rat brain using BECN1 Monoclonal Antibody at dilution of 1:2000.
2 / 2
Immunohistochemistry of paraffin-embedded Human breast carcinoma tissue using BECN1 Monoclonal Antibody at dilution of 1:200.

Western Blot analysis of 1) 293T, 2) C2C12, 3) Rat brain using BECN1 Monoclonal Antibody at dilution of 1:2000.
Immunohistochemistry of paraffin-embedded Human breast carcinoma tissue using BECN1 Monoclonal Antibody at dilution of 1:200.

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E-AB-22139-20uL20uL£125.00
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E-AB-22139-60uL60uL£172.00
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E-AB-22139-120uL120uL£237.00
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E-AB-22139-200uL200uL£344.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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  • Further Information
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Further Information

Abbreviation:
BECN1
Background:
Beclin-1 (BECN1), also known as ATG6 or VPS30, has a central role in autophagy, a process of programmed cell survival, which is increased during periods of cell stress and extinguished during the cell cycle. Beclin-1, may play a role in antiviral host defense. It protects against infection by a neurovirulent strain of Sindbis virus. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. A progressively reduced Beclin-1 expression is reported to correlate with the primary tumor growth of squamous cell carcinoma and adenocarcinoma of the lung. Caspase-mediated cleavage of Beclin 1 promotes crosstalk between apoptosis and autophagy.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-2000, IHC 1:100-200
Immunogen:
Synthetic Peptide of Beclin-1
ObservedMW:
60kDa
Purification method:
Protein A purification
Target Synonym:
APG6;ATG 6;ATG6;ATG6 autophagy related 6 homolog;Bcl-2-interacting protein beclin;Beclin 1 (coiled coil moesin like BCL2 interacting protein);Beclin 1 autophagy related;Beclin-1;Beclin1;BECN 1;Becn1;BECN1;Coiled coil myosin like BCL2 interacting protein;Coiled-coil myosin-like BCL2-interacting protein;GT197;Protein GT197;VPS 30;VPS30
UNIProt ID:
Q14457

Documents

References

  • https://www.mdpi.com/2227-9059/10/5/1092
  • https://www.frontiersin.org/articles/10.3389/fonc.2019.01469/full