Elabscience

Recombinant Mouse GM-CSF/CSF2 Protein (His Tag)(Active)

Product Code:
 
PKSM041032
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Mouse
Regulatory Status:
 
RUO
Application:
 
Cell Culture
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Store at < -20°C stable for 6 months after receipt. Please minimize freeze-thaw cycles.
 

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CodeSizePrice
PKSM041032-10ug10ug£219.00
Quantity:
PKSM041032-50ug50ug£497.00
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Further Information

Abbreviation:
GM-CSF;CSF2
Accession:
P01587
Activity:
Measured in a cell proliferation assay using PDC-P1 cells. The ED50 for this effect is 40-170 pg/ml.
Background:
Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factorthat can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by anumber of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cellsand fibroblasts) in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophageprogenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. Onmature hematopoietic, monocytes/ macrophages and eosinophils. GM-CSF has a functional role on nonhematopoitic cells. It can induce human endothelial cells to migrate and proliferate. Additionally, GM-CSF canalso stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma andadenocarcinoma cell lines.
Calculated MW:
15.1 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-6His
ObservedMW:
18-30 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Ala18-Lys141
Target Synonym:
Granulocyte-Macrophage Colony-Stimulating Factor;GM-CSF;Colony-Stimulating Factor;CSF;Molgramostin;Sargramostim;CSF2;GMCSF
UNIProt ID:
P01587

Documents