Recombinant Mouse S100A8/CAGA Protein (His Tag)

S100A8;CAGA

P27005

Protein S100-A8(Mrp8) contains 2 EF-hand domains and belongs to the S-100 family. Mrp8 binds two calcium ions per molecule with an affinity similar to that of the S-100 proteins. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. It may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis.

11.3 kDa

< 1.0 EU per ug of the protein as determined by the LAL method.

E.coli

Lyophilized from a 0.2 um filtered solution of 20mMTris,pH8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

C-6His

13 kDa

> 95 % as determined by reducing SDS-PAGE.

Met1-Glu89

Protein S100-A8;Calgranulin-A;Chemotactic cytokine CP-10;Leukocyte L1 complex light chain;Migration inhibitory factor-related protein 8;MRP-8;Pro-inflammatory S100 cytokine;S100 calcium-binding protein A8;S100a8;Caga;Mrp8;60B8Ag;AI323541;B8Ag;Caga;CFAg;CP-10;p8

P27005