Elabscience

CD284 Polyclonal Antibody

Product Code:
 
E-AB-70375
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunohistochemistry analysis of paraffin-embedded mouse spleen using CD284 Polyclonal Antibody at dilution of 1:1000.
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Immunohistochemistry analysis of paraffin-embedded mouse spleen using CD284 Polyclonal Antibody at dilution of 1:1000.

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E-AB-70375-200uL200uL£351.00
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  • Further Information
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Further Information

Abbreviation:
CD284
Background:
TLR4,also named as CD284,belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88,TIRAP and TRAF6,leading to NF-kappa-B activation,cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Calculated MW:
95kDa
Concentration:
0.9 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1::500-1:2000
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse TLR4.
ObservedMW:
95kDa
Purification method:
Affinity purification
Target Synonym:
ARMD10;CD284;CD284 antigen;Homolog of Drosophila toll;hToll;TLR 4;TLR4;TLR4;TOLL;Toll like receptor 4;Toll-like receptor 4
UNIProt ID:
O00206,Q9QUK6,Q9QX05

Documents

References

  • https://www.sciencedirect.com/science/article/pii/S0024320521008626
  • https://academic.oup.com/jpp/article-abstract/73/4/473/6118677