Elabscience

CD59 Polyclonal Antibody

Product Code:
 
E-AB-64157
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of various cell lines using CD59 Polyclonal Antibody at dilution of 1:1000.
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Western blot analysis of extracts of various cell lines using CD59 Polyclonal Antibody at dilution of 1:1000.

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CodeSizePrice
E-AB-64157-60uL60uL£210.00
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E-AB-64157-120uL120uL£291.00
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E-AB-64157-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
CD59
Background:
This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
14kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human CD59 (NP_001120695.1).
ObservedMW:
14kDa
Purification method:
Affinity purification
Target Synonym:
CD59;16.3A5;1F5;EJ16;EJ30;EL32;G344;HRF-20;HRF20;MAC-IP;MACIF;MEM43;MIC11;MIN1;MIN2;MIN3;MIRL;MSK21;p18-20
UNIProt ID:
P13987

Documents