Elabscience

CNOT8 Polyclonal Antibody

Product Code:
 
E-AB-62996
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of various cell lines using CNOT8 Polyclonal Antibody at 1:1000 dilution.
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Western blot analysis of extracts of various cell lines using CNOT8 Polyclonal Antibody at 1:1000 dilution.

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E-AB-62996-60uL60uL£210.00
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E-AB-62996-120uL120uL£291.00
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E-AB-62996-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
CNOT8
Background:
Has 3'-5' poly(A exoribonuclease activity for synthetic poly(A RNA substrate. Its function seems to be partially redundant with that of CNOT7. Catalytic component of the CCR4-NOT complex which is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
21kDa/27kDa/33kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human CNOT8
ObservedMW:
34kDa
Purification method:
Affinity purification
Target Synonym:
CNOT8;CAF1;CALIF;Caf1b;POP2;hCAF1
UNIProt ID:
Q9UFF9

Documents