Elabscience

GRM1 Polyclonal Antibody

Product Code:
 
E-AB-63478
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of Rat liver using GRM1 Polyclonal Antibody at dilution of 1:1000.
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Western blot analysis of extracts of Rat liver using GRM1 Polyclonal Antibody at dilution of 1:1000.

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E-AB-63478-60uL60uL£210.00
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E-AB-63478-120uL120uL£291.00
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E-AB-63478-200uL200uL£431.00
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Further Information

Abbreviation:
GRM1
Background:
This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
101kDa/132kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human GRM1 (NP_001264993.1).
ObservedMW:
132kDa
Purification method:
Affinity purification
Target Synonym:
GRM1;GPRC1A;MGLU1;MGLUR1;PPP1R85;SCAR13
UNIProt ID:
Q13255

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