Elabscience

GTF2A2 Polyclonal Antibody

Product Code:
 
E-AB-62777
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of NCI-H460 cells using GTF2A2 Polyclonal Antibody at dilution of 1:1000.
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Western blot analysis of extracts of NCI-H460 cells using GTF2A2 Polyclonal Antibody at dilution of 1:1000.

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E-AB-62777-60uL60uL£210.00
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E-AB-62777-200uL200uL£431.00
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Further Information

Abbreviation:
GTF2A2
Background:
Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and the general initiation factors TFIIA, TFIIB (MIM 189963), TFIID (MIM 313650), TFIIE (MIM 189962), TFIIF (MIM 189968), TFIIG/TFIIJ, and TFIIH (MIM 189972). The first step involves recognition of the TATA element by the TATA-binding subunit (TBP; MIM 600075) and may be regulated by TFIIA, a factor that interacts with both TBP and a TBP-associated factor (TAF; MIM 600475) in TFIID. TFIIA has 2 subunits (43 and 12 kD) in yeast and 3 subunits in higher eukaryotes. In HeLa extracts, it consists of a 35-kD alpha subunit and a 19-kD beta subunit encoded by the N- and C-terminal regions of GTF2A1 (MIM 600520), respectively, and a 12-kD gamma subunit encoded by GTF2A2 (DeJong et al., 1995 [PubMed 7724559]).
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
12kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human GTF2A2 (NP_004483.1).
ObservedMW:
12kDa
Purification method:
Affinity purification
Target Synonym:
GTF2A2;HsT18745;T18745;TF2A2;TFIIA;TFIIA-12;TFIIA-gamma;TFIIAS
UNIProt ID:
P52657

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