Elabscience

JNK1/2/3 Polyclonal Antibody

Product Code:
 
E-AB-70345
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Mouse
  • Rat
Application:
 
Immunohistochemistry (IHC)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunohistochemistry analysis of paraffin-embedded Mouse brain using JNK1/2/3 Polyclonal Antibody at dilution of 1:200.
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Immunohistochemistry analysis of paraffin-embedded Mouse brain using JNK1/2/3 Polyclonal Antibody at dilution of 1:200.

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E-AB-70345-60uL60uL£184.00
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E-AB-70345-120uL120uL£251.00
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E-AB-70345-200uL200uL£351.00
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This product comes from: China.
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Further Information

Abbreviation:
JNK1/2/3
Background:
c-Jun N-terminal kinases (JNKs) phosphorylate and augment transcriptional activity of c-Jun. JNKs originate from three genes that yield ten isoforms through alternative mRNA splicing, including JNK1α1,JNK1β1, JNK2α1, JNK2β1 and JNK3α1, which represent the p46 isoforms, and JNK1α2, JNK1β2, JNK2α2, JNK2β2 and JNK3β2, which represent the p54 isoforms. JNKs coordinate cell responses to stress and influence regulation of cell growth and ransformation. The human JNK1 (PRKM8, SAPK1, MAPK8) gene maps to chromosome 10q11.22 and shares 83% amino acid identity with JNK2. JNK1 is necessary for normal activation and differentiation of CD4 helper T (TH) cells into TH1 and TH2 effector cells. Capsaicin activates JNK1 and p38 in Ras-transformed human breast epithelial cells. Nitrogen oxides (NOx) upregulate JNK1 in addition to c-Fos, c-Jun and other signaling kinases, including MEKK1 and p38.
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Concentration:
400 ug/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:200-1:500
Immunogen:
KLH conjugated Synthetic peptide corresponding to human JNK1
Purification method:
Affinity purification
Target Synonym:
MAPK8;JNK1;PRKM8;SAPK1;SAPK1C;Mitogen-activated protein kinase 8;MAP kinase 8;MAPK 8;JNK-46;Stress-activated protein kinase 1c;SAPK1c;Stress-activated protein kinase JNK1;c-Jun N-terminal kinase 1;MAPK9;JNK2;PRKM9;SAPK1A;Mi
UNIProt ID:
Q91Y86,Q9WTU6,Q61831

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