Elabscience

MBNL1 Polyclonal Antibody

Product Code:
 
E-AB-62123
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of various cell lines using MBNL1 Polyclonal Antibody at dilution of 1:1000.
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Western blot analysis of extracts of various cell lines using MBNL1 Polyclonal Antibody at dilution of 1:1000.

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CodeSizePrice
E-AB-62123-60uL60uL£210.00
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E-AB-62123-120uL120uL£291.00
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E-AB-62123-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
MBNL1
Background:
This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
33kDa/34kDa/36kDa/37kDa/39kDa/40kDa/41kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100
Immunogen:
Recombinant fusion protein of human MBNL1 (NP_066368.2).
ObservedMW:
42kDa
Purification method:
Affinity purification
Target Synonym:
MBNL1;EXP;MBNL
UNIProt ID:
Q9NR56

Documents