Elabscience

MDC1 Polyclonal Antibody

Product Code:
 
E-AB-63008
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunohistochemistry of paraffin-embedded Human colon carcinoma using MDC1 Polyclonal Antibody at dilution of 1:100 (40x lens).
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Immunofluorescence analysis of U-2 OS cells using MDC1 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
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Immunohistochemistry of paraffin-embedded Human colon carcinoma using MDC1 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis of U-2 OS cells using MDC1 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

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E-AB-63008-60uL60uL£210.00
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E-AB-63008-120uL120uL£291.00
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E-AB-63008-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
MDC1
Background:
The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-1:200 IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human MDC1 (NP_055456.2).
Purification method:
Affinity purification
Target Synonym:
MDC1;NFBD1
UNIProt ID:
Q14676

Documents