Elabscience

SIM2 Polyclonal Antibody

Product Code:
 
E-AB-65198
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of various cell lines using SIM2 Polyclonal Antibody at dilution of 1:1000.
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Western blot analysis of extracts of various cell lines using SIM2 Polyclonal Antibody at dilution of 1:1000.

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CodeSizePrice
E-AB-65198-60uL60uL£210.00
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E-AB-65198-120uL120uL£291.00
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E-AB-65198-200uL200uL£431.00
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Further Information

Abbreviation:
SIM2
Background:
This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
63kDa/73kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human SIM2 (NP_033664.2).
ObservedMW:
56kDa
Purification method:
Affinity purification
Target Synonym:
SIM2;HMC13F06;HMC29C01;SIM;bHLHe15
UNIProt ID:
Q14190

Documents