Elabscience

XRCC5 Polyclonal Antibody

Product Code:
 
E-AB-64590
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Immunohistochemistry (IHC)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunohistochemistry of paraffin-embedded Human esophagus using XRCC5 Polyclonal Antibody at dilution of  1:100 (40x lens).

Immunohistochemistry of paraffin-embedded Human esophagus using XRCC5 Polyclonal Antibody at dilution of  1:100 (40x lens).

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E-AB-64590-200uL200uL£431.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
XRCC5
Background:
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant fusion protein of human XRCC5 (NP_066964.1).
Purification method:
Affinity purification
Target Synonym:
XRCC5;KARP-1;KARP1;KU80;KUB2;Ku86;NFIV
UNIProt ID:
P13010

Documents

References

  • https://www.ncbi.nlm.nih.gov/pmc/articles/pmc8139207/