Elabscience

AF/LE Purified Anti-Mouse F4/80 Antibody[CI:A3-1]

Product Code:
 
E-AB-F09950
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rat
Antibody Isotype:
 
Rat IgG2b, κ
Antibody Clone:
 
CI:A3-1
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Applications:
  • Depletion
  • Flow Cytometry
  • Functional Study
Shipping:
 
Ice packs
Storage:
 
Store at 2-8°C. Do not freeze.
 

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CodeSizePrice
E-AB-F09950-50ug50ug£140.00
Quantity:
E-AB-F09950-500ug500ug£341.00
Quantity:
E-AB-F09950-1mg1mg£475.00
Quantity:
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This product comes from: China.
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Further Information

Abbreviation:
F4/80
Background:
F4/80 is < 160 kD glycoprotein. It is characterized as a member of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family. F4/80, also known as EMR1 or Ly71, has been widely used as a murine macrophage marker, which is expressed on the majority of tissue macrophages including peritoneal macrophages, macrophages in lung, gut, thymus and red pulp of spleen (but not on the macrophages located in T cell areas of the spleen, lymph node and Peyer's patch), Kuffer cells, Langerhans cells, and bone marrow stromal cells. F4/80 has also been shown on a subset of dendritic cells. The biological ligand of F4/80 has not been identified, but it has been reported that F4/80 is required for induction of CD8+ T cells-mediated peripheral tolerance.
Buffer:
0.2 um filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Concentration:
0.5 mg/mL
Conjugation:
None (Purified antibody-Azide Free/Low endotoxin)
GeneID:
13733
Target Synonym:
Adhesion G protein-coupled receptor E1;Adgre1;Cell surface glycoprotein F4/80;EGF-like module receptor 1;Adgre1;Emr1; Gpf480;
UNIProt ID:
Q61549
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is < 1.0 ug per 10^6 cells in 100 uL volume or 100 uL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

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