Elabscience

Elab Fluor® 488 Anti-Mouse CD54 Antibody[YN1/1.7.4]

Product Code:
 
E-AB-F1018UL
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rat
Antibody Isotype:
 
Rat IgG2b, κ
Antibody Clone:
 
YN1/1.7.4
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Flow Cytometry
Shipping:
 
Ice packs
Storage:
 
Store at 2-8°C and protected from prolonged exposure to light. Do not freeze.
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C57BL/6 murine splenocytes are stained with Elab Fluor® 488 Anti-Mouse CD54 Antibody (filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.
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C57BL/6 murine splenocytes are stained with Elab Fluor® 488 Anti-Mouse CD54 Antibody (filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.

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CodeSizePrice
E-AB-F1018UL-25ug25ug£130.00
Quantity:
E-AB-F1018UL-100ug100ug£204.00
Quantity:
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This product comes from: China.
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Further Information

Abbreviation:
CD54
Background:
CD54 is a 90 kD immunoglobulin superfamily member also known as ICAM-1 and Ly-47. It is expressed on activated endothelial cells, high endothelial venules (HEV), T and B cells, monocytes/ macrophages, granulocytes, and dendritic cells. CD54 is an important intracellular adhesion molecule that participates in T cell-T cell, T cell-B cell, and T cell-target cell interactions via binding of LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). CD54 has also been shown to be involved in lymphocyte trafficking, making it an important molecule in many immune reactions and inflammation. CD54 is also a receptor for rhinovirus. The YN1/1.7.4 antibody has been reported to block binding of mouse CD54 to LFA-1 and Mac-1, inhibit cell-cell adhesion, and function in antigen presentation to T cells and leukocyte migration to inflammatory tissues.
Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Concentration:
0.5 mg/mL
Conjugation:
Elab Fluor® 488
GeneID:
15894
Target Synonym:
Intercellular adhesion molecule 1;Icam1;MALA-2;MyD10;CD54;Icam-1;
UNIProt ID:
P13597
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 ug/10^6 cells in 100 uL volume].

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